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doi: 10.1093/schbul/sbw038

These symptoms can indirectly affect body weight because low energy often reduces appetite and activity

583 In addition to the traditionally recognized loss of dopaminergic neurons in the substantia nigra and intracellular alpha-synuclein (-syn) deposition, the brains of PD patients exhibit iron deposition, heightened oxidative stress, and lipid peroxidation damage

While the archaea consume the hydrogen gas which might theoretically reduce total gas volume, our experience clinically is that methane SIBO clients tend to have more sustained bloating